CCN 2026 | Tutorial: State-Space Modelling for Human Neuroscience

CCN 2026 | Tutorial: State-Space Modelling for Human Neuroscience

🎙 Luiz Pessoa, Harrison Ritz 👥 4K 📅 August 12, 2026 ⏱ 107 min 👁 96 📄 tutorial 🧭 2026-08-15
Available in: English (current) Français

Keywords

state-space modelsKalman filterexpectation maximizationlinear dynamical systemsswitching linear dynamical systems

Summary

This tutorial, presented by Luiz Pessoa and Harrison Ritz at CCN 2026, introduces state-space models (SSMs) as a framework for analyzing human neuroscience data. The presenters emphasize a ‘dynamics-first’ approach, unifying how information is encoded, exchanged, and modulated across brain areas. They begin with theoretical foundations, explaining Bayesian filtering and expectation maximization (EM) as core inference methods. They then demonstrate the application of linear dynamical systems (LDS) to simulated data, highlighting the interpretability and power of these models. The tutorial culminates in an advanced example using switching linear dynamical systems (SLDS) to analyze HCP resting-state fMRI data, revealing many-to-many relationships between brain states and functional connectivity networks. Throughout, they provide practical guidance, including code demonstrations in Python (using Dynamax) and Julia, and emphasize the importance of understanding the underlying mathematics. The tutorial is designed to be a lasting resource, with links to GitHub notebooks and references. The presenters also discuss the advantages of SSMs over traditional methods like PCA or HMMs, and their potential for capturing continuous dynamics and autocorrelation in neural data.

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Critical Evaluation

Value of the Information & Strength of the Argument

The tutorial provides substantial value by offering a clear, step-by-step introduction to state-space modeling, a powerful but often underutilized approach in cognitive neuroscience. The argumentation is solid: the presenters justify the use of SSMs by highlighting their ability to model latent dynamics, handle noise, and provide interpretable parameters. They contrast SSMs with simpler methods like PCA and HMMs, explaining why the added complexity is beneficial. The presentation is well-structured, moving from theory to practical implementation, and includes concrete examples from EEG and fMRI. The emphasis on understanding the math behind the methods, even when using high-level packages, strengthens the educational value. The tutorial also acknowledges limitations, such as the point-estimate nature of EM, and encourages a Bayesian perspective where possible.

Scientific Rigor, Source Quality, Title Accuracy

The tutorial demonstrates scientific rigor by grounding the methods in established literature, referencing key papers and researchers in the field. The presenters are credible experts, and the content aligns with current best practices in computational neuroscience. The title accurately reflects the content, and the tutorial’s structure is logical and well-paced. The inclusion of practical resources, such as GitHub notebooks and references, enhances its reliability. However, as a tutorial, it does not present new empirical findings, and the reliance on the presenters’ own packages introduces a potential bias, though they acknowledge this. Overall, the sources are appropriate and the content is trustworthy.

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Title / Content Match

The title accurately reflects the content: a tutorial on state-space modeling applied to human neuroscience.

Quality & Reliability

8/10

The tutorial is presented by leading researchers in computational neuroscience, with a clear pedagogical structure and references to established methods. The content is technically accurate and aligns with current literature, though it is an introductory tutorial and not a peer-reviewed study.

Key Moments

Cited Sources

Concurring Sources

  • A unifying review of linear Gaussian models — Referenced in the tutorial as a key review for understanding the family of linear Gaussian models.
  • Dynamax (Python library) — Mentioned as a tool for implementing state-space models.

Contribution & Novelties

This tutorial provides a comprehensive and accessible introduction to state-space modeling for human neuroscience, bridging a gap between systems neuroscience and cognitive neuroscience. It emphasizes a ‘dynamics-first’ perspective, advocating for the use of SSMs to unify encoding, connectivity, and context-dependent modulation. The tutorial offers practical code examples and resources, making it a valuable educational tool. It also highlights recent applications, such as using SLDS to reveal many-to-many relationships between brain states and functional networks, which is a novel contribution to the field.

Pour aller plus loin :

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Radar Profile

The radar chart shows a balanced profile with high scores in information quantity, quality, and reliability, and a slightly lower but still strong score in technical level. This indicates a well-rounded tutorial that is both informative and technically sound, suitable for an audience with some background in neuroscience and statistics.

Reliability 8/10

💬 No comments were provided for analysis.