Lecture -1 MOLECULAR BASIS OF INHERITANCE | By Dr Rajesh sir

This lecture, presented by Dr. Rajesh Tokriya, introduces the chapter ‘Molecular Basis of Inheritance’ for Class 12 and NEET aspirants. The instructor begins with a motivational talk, emphasizing the importance of hard work and dedication. He then explains the basic concept of inheritance, defining it as the transfer of parental characters to offspring. The lecture covers the historical background, mentioning Friedrich Miescher’s discovery of DNA in 1869, Richard Altmann’s finding that nucleic acids are acidic, and Robert Feulgen’s development of staining techniques. The composition of nucleic acids is detailed, explaining that nucleotides consist of a sugar, a nitrogenous base, and a phosphate group. The differences between DNA and RNA are highlighted, including the presence of deoxyribose sugar in DNA and ribose in RNA, and the absence of uracil in DNA and thymine in RNA. The lecture also touches on the contributions of Rosalind Franklin and Maurice Wilkins to DNA structure discovery. The content is presented in a simplified, exam-oriented manner, with emphasis on remembering key points for NEET.