Approach to Resistant Hypertension

Approach to Resistant Hypertension

by Dr Lehlonono Seema

Life & Natural Systems Medicine & Health MMedicine and NursingMJDCardiovascular medicine
🎙 Dr Lehlonono Seema 👥 2K 📅 July 22, 2026 ⏱ 30 min 👁 102 📄 expert opinion 🧭 2026-08-15
Available in: English (current) Français

Keywords

resistant hypertensionESC guidelinessecondary hypertensionspironolactonerenal denervation

Summary

This presentation from an internal medicine academic meeting reviews the approach to resistant hypertension, focusing on the 2024/2025 ESC guidelines. It begins with a clinical case of a 31-year-old male with severe hypertension, obesity, OSA phenotype, and established CKD, illustrating the challenges in management. The talk covers epidemiology, pathogenesis, diagnosis, risk stratification, and complications. Key points include the definition of resistant hypertension (uncontrolled BP on three agents including a diuretic), the importance of excluding pseudo-resistance (adherence, white coat, measurement errors), and the evaluation for secondary causes. Treatment strategies emphasize lifestyle modification, optimization of medical therapy, and the addition of spironolactone (class 2A). Novel therapies and interventional options like renal denervation are discussed. The presentation underscores the need for a patient-centered, multidisciplinary approach.

122 words

Critical Evaluation

Value of the Information & Strength of the Argument

The presentation provides a solid overview of resistant hypertension, grounded in a real clinical case. The argumentation is logical, moving from case presentation to definition, diagnosis, and management. It emphasizes the importance of excluding pseudo-resistance and secondary causes, which is crucial. The discussion of treatment options, including spironolactone and novel therapies, is evidence-based, though the presenter acknowledges limited personal experience with newer agents. The case-based approach enhances practical relevance.

Scientific Rigor, Source Quality, Title Accuracy

The presentation is based on the 2024/2025 ESC guidelines, which are authoritative. However, no specific citations or references are provided in the video or description, limiting verifiability. The title accurately reflects the content. The presenter is a cardiology fellow, and the talk is part of an academic meeting, suggesting a reasonable level of expertise. No external sources are cited, so the quality of sources is moderate.

150 words

Title / Content Match

The title accurately reflects the content, which is a comprehensive review of resistant hypertension.

Quality & Reliability

7/10

Presentation by a cardiology fellow at an academic meeting, based on ESC guidelines, with a clinical case. No disclosures, but no external sources cited beyond guidelines.

Key Moments

Markers derived by PSI from the transcript: the creator did not define chapters.

Cited Sources

  • 2024 ESC Guidelines for the management of elevated blood pressure and hypertension — Referenced as the basis for the approach to resistant hypertension

Concurring Sources

  • 2024 ESC Guidelines for the management of elevated blood pressure and hypertension — The presentation aligns with the ESC guidelines.

Contribution & Novelties

The presentation offers a practical, case-based approach to resistant hypertension, emphasizing the importance of excluding pseudo-resistance and secondary causes. It highlights the role of spironolactone and discusses novel therapies and renal denervation. The ‘Pour aller plus loin’ section provides additional resources.

Pour aller plus loin :

  • 2024 ESC Guidelines — Official guidelines for hypertension management.
  • Resistant hypertension: diagnosis, evaluation, and treatment — AHA scientific statement.
  • Renal denervation for hypertension — Recent trial results.

73 words

Radar Profile

The radar profile shows high scores in quantity and technical level, with moderate quality and reliability. This indicates a comprehensive but not deeply sourced presentation.

Reliability 7/10